As adolescents, they underwent functional MRIs while completing a task to measure their brains’ reaction in anticipating rewards - in this case, trying to win money. “To show any relation with increases in depressive symptoms over time, we have to follow subjects for decades because full-blown syndromes usually do not emerge until young adulthood,” she said.Īs young children, the subjects were categorized as either inhibited or uninhibited. Tang’s research is unique for its characterization of the patients’ early temperamental risks as well as the length of time they were studied. But we do know that people who have had an anxiety disorder are 50% to 60% more likely to have depression later in life, so inhibited children should have a higher risk for depression as well.” “Less has been known about depression, which generally has a later onset, in young adulthood. “We know that inhibited children are more likely to have anxiety disorders later, particularly social anxiety, that begins in late childhood to adolescence,” Tang said. This distinction defines uninhibited versus inhibited behavior. When newborns are introduced to new objects, people, or situations, some react favorably and approach them without fear, while others react with caution or avoidance. “These results could inform the development of prevention-oriented treatments tailored to the individual.” Publisher’s web page for publicity information, book ordering and selected news media coverage.“The findings highlight different mechanisms in the brain and relate them to who is at greater risk for developing different mental health issues,” said Tang, who conducted the research at the University of Maryland, College Park, before joining UT Dallas in August.
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